Hydrogen sulfide alleviates cadmium toxicity through regulations of cadmium transport across the plasma and vacuolar membranes in Populus euphratica cells.
Identifieur interne : 002648 ( Main/Exploration ); précédent : 002647; suivant : 002649Hydrogen sulfide alleviates cadmium toxicity through regulations of cadmium transport across the plasma and vacuolar membranes in Populus euphratica cells.
Auteurs : Jian Sun [République populaire de Chine] ; Ruigang Wang ; Xuan Zhang ; Yicheng Yu ; Rui Zhao ; Zongyun Li ; Shaoliang ChenSource :
- Plant physiology and biochemistry : PPB [ 1873-2690 ] ; 2013.
Descripteurs français
- KwdFr :
- Cadmium (métabolisme), Cadmium (toxicité), Membrane cellulaire (effets des médicaments et des substances chimiques), Membrane cellulaire (métabolisme), Membranes intracellulaires (effets des médicaments et des substances chimiques), Membranes intracellulaires (métabolisme), Populus (effets des médicaments et des substances chimiques), Populus (métabolisme), Sulfure d'hydrogène (pharmacologie), Vacuoles (effets des médicaments et des substances chimiques), Vacuoles (métabolisme).
- MESH :
- effets des médicaments et des substances chimiques : Membrane cellulaire, Membranes intracellulaires, Populus, Vacuoles.
- métabolisme : Cadmium, Membrane cellulaire, Membranes intracellulaires, Populus, Vacuoles.
- pharmacologie : Sulfure d'hydrogène.
- toxicité : Cadmium.
English descriptors
- KwdEn :
- Cadmium (metabolism), Cadmium (toxicity), Cell Membrane (drug effects), Cell Membrane (metabolism), Hydrogen Sulfide (pharmacology), Intracellular Membranes (drug effects), Intracellular Membranes (metabolism), Populus (drug effects), Populus (metabolism), Vacuoles (drug effects), Vacuoles (metabolism).
- MESH :
- chemical , metabolism : Cadmium.
- chemical , pharmacology : Hydrogen Sulfide.
- chemical , toxicity : Cadmium.
- drug effects : Cell Membrane, Intracellular Membranes, Populus, Vacuoles.
- metabolism : Cell Membrane, Intracellular Membranes, Populus, Vacuoles.
Abstract
Hydrogen sulfide (H2S) is emerging as a novel signalling molecule involved in plant growth and responses against abiotic stresses. However, little information is known about its role in cadmium (Cd) detoxification. In the present study, the effects of H2S on Cd toxicity were investigated in Populus euphratica cells using fluorescence imaging technique and a non-invasive vibrating ion-selective microelectrode. Pretreatment with a H2S donor, sodium hydrosulfide (NaHS), significantly mitigated the Cd-induced programmed cell death in P. euphratica cells. The alleviation effect of NaHS was more pronounced at 50-100 μM as compared to low (25 μM) and high doses (200 μM). Under Cd stress, total activities of antioxidant enzymes, such as ascorbate peroxidase, catalase and glutathione reductase, were significantly enhanced in NaHS-treated cells, leading to a decline of H2O2 accumulation and lipid peroxidation. Moreover, NaHS reduced Cd accumulation in the cytoplasm but increased the fraction of Cd in the vacuole. Cd flux profiles revealed that H2S inhibited the Cd influx through the plasma membrane (PM) calcium channels that activated by H2O2. NaHS enhanced Cd influx into the vacuole, and the Cd influx was dependent on the pH gradients across the tonoplast. Taken together, these results suggest that H2S alleviates Cd toxicity via the improvement of antioxidant system and cellular Cd homeostasis. The up-regulation of antioxidant enzymes by H2S reduced the accumulation of H2O2, and thus decreased Cd influx through the H2O2-activated PM calcium channels. The H2S-simulated vacuolar Cd sequestration was presumably due to the activation of tonoplast Cd(2+)/H(+) antiporters.
DOI: 10.1016/j.plaphy.2013.01.003
PubMed: 23416498
Affiliations:
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sortKey="Zhang, Xuan" sort="Zhang, Xuan" uniqKey="Zhang X" first="Xuan" last="Zhang">Xuan Zhang</name></author><author><name sortKey="Yu, Yicheng" sort="Yu, Yicheng" uniqKey="Yu Y" first="Yicheng" last="Yu">Yicheng Yu</name></author><author><name sortKey="Zhao, Rui" sort="Zhao, Rui" uniqKey="Zhao R" first="Rui" last="Zhao">Rui Zhao</name></author><author><name sortKey="Li, Zongyun" sort="Li, Zongyun" uniqKey="Li Z" first="Zongyun" last="Li">Zongyun Li</name></author><author><name sortKey="Chen, Shaoliang" sort="Chen, Shaoliang" uniqKey="Chen S" first="Shaoliang" last="Chen">Shaoliang Chen</name></author></analytic><series><title level="j">Plant physiology and biochemistry : PPB</title><idno type="eISSN">1873-2690</idno><imprint><date when="2013" type="published">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Cadmium (metabolism)</term><term>Cadmium (toxicity)</term><term>Cell Membrane (drug effects)</term><term>Cell Membrane (metabolism)</term><term>Hydrogen Sulfide (pharmacology)</term><term>Intracellular Membranes (drug effects)</term><term>Intracellular Membranes (metabolism)</term><term>Populus (drug effects)</term><term>Populus (metabolism)</term><term>Vacuoles (drug effects)</term><term>Vacuoles (metabolism)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Cadmium (métabolisme)</term><term>Cadmium (toxicité)</term><term>Membrane cellulaire (effets des médicaments et des substances chimiques)</term><term>Membrane cellulaire (métabolisme)</term><term>Membranes intracellulaires (effets des médicaments et des substances chimiques)</term><term>Membranes intracellulaires (métabolisme)</term><term>Populus (effets des médicaments et des substances chimiques)</term><term>Populus (métabolisme)</term><term>Sulfure d'hydrogène (pharmacologie)</term><term>Vacuoles (effets des médicaments et des substances chimiques)</term><term>Vacuoles (métabolisme)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Cadmium</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Hydrogen Sulfide</term></keywords><keywords scheme="MESH" type="chemical" qualifier="toxicity" xml:lang="en"><term>Cadmium</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Cell Membrane</term><term>Intracellular Membranes</term><term>Populus</term><term>Vacuoles</term></keywords><keywords scheme="MESH" qualifier="effets des médicaments et des substances chimiques" xml:lang="fr"><term>Membrane cellulaire</term><term>Membranes intracellulaires</term><term>Populus</term><term>Vacuoles</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Cell Membrane</term><term>Intracellular Membranes</term><term>Populus</term><term>Vacuoles</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Cadmium</term><term>Membrane cellulaire</term><term>Membranes intracellulaires</term><term>Populus</term><term>Vacuoles</term></keywords><keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Sulfure d'hydrogène</term></keywords><keywords scheme="MESH" qualifier="toxicité" xml:lang="fr"><term>Cadmium</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Hydrogen sulfide (H2S) is emerging as a novel signalling molecule involved in plant growth and responses against abiotic stresses. However, little information is known about its role in cadmium (Cd) detoxification. In the present study, the effects of H2S on Cd toxicity were investigated in Populus euphratica cells using fluorescence imaging technique and a non-invasive vibrating ion-selective microelectrode. Pretreatment with a H2S donor, sodium hydrosulfide (NaHS), significantly mitigated the Cd-induced programmed cell death in P. euphratica cells. The alleviation effect of NaHS was more pronounced at 50-100 μM as compared to low (25 μM) and high doses (200 μM). Under Cd stress, total activities of antioxidant enzymes, such as ascorbate peroxidase, catalase and glutathione reductase, were significantly enhanced in NaHS-treated cells, leading to a decline of H2O2 accumulation and lipid peroxidation. Moreover, NaHS reduced Cd accumulation in the cytoplasm but increased the fraction of Cd in the vacuole. Cd flux profiles revealed that H2S inhibited the Cd influx through the plasma membrane (PM) calcium channels that activated by H2O2. NaHS enhanced Cd influx into the vacuole, and the Cd influx was dependent on the pH gradients across the tonoplast. Taken together, these results suggest that H2S alleviates Cd toxicity via the improvement of antioxidant system and cellular Cd homeostasis. The up-regulation of antioxidant enzymes by H2S reduced the accumulation of H2O2, and thus decreased Cd influx through the H2O2-activated PM calcium channels. The H2S-simulated vacuolar Cd sequestration was presumably due to the activation of tonoplast Cd(2+)/H(+) antiporters.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">23416498</PMID><DateCompleted><Year>2013</Year><Month>09</Month><Day>05</Day></DateCompleted><DateRevised><Year>2020</Year><Month>09</Month><Day>30</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1873-2690</ISSN><JournalIssue CitedMedium="Internet"><Volume>65</Volume><PubDate><Year>2013</Year><Month>Apr</Month></PubDate></JournalIssue><Title>Plant physiology and biochemistry : PPB</Title><ISOAbbreviation>Plant Physiol Biochem</ISOAbbreviation></Journal><ArticleTitle>Hydrogen sulfide alleviates cadmium toxicity through regulations of cadmium transport across the plasma and vacuolar membranes in Populus euphratica cells.</ArticleTitle><Pagination><MedlinePgn>67-74</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.plaphy.2013.01.003</ELocationID><ELocationID EIdType="pii" ValidYN="Y">S0981-9428(13)00022-3</ELocationID><Abstract><AbstractText>Hydrogen sulfide (H2S) is emerging as a novel signalling molecule involved in plant growth and responses against abiotic stresses. However, little information is known about its role in cadmium (Cd) detoxification. In the present study, the effects of H2S on Cd toxicity were investigated in Populus euphratica cells using fluorescence imaging technique and a non-invasive vibrating ion-selective microelectrode. Pretreatment with a H2S donor, sodium hydrosulfide (NaHS), significantly mitigated the Cd-induced programmed cell death in P. euphratica cells. The alleviation effect of NaHS was more pronounced at 50-100 μM as compared to low (25 μM) and high doses (200 μM). Under Cd stress, total activities of antioxidant enzymes, such as ascorbate peroxidase, catalase and glutathione reductase, were significantly enhanced in NaHS-treated cells, leading to a decline of H2O2 accumulation and lipid peroxidation. Moreover, NaHS reduced Cd accumulation in the cytoplasm but increased the fraction of Cd in the vacuole. Cd flux profiles revealed that H2S inhibited the Cd influx through the plasma membrane (PM) calcium channels that activated by H2O2. NaHS enhanced Cd influx into the vacuole, and the Cd influx was dependent on the pH gradients across the tonoplast. Taken together, these results suggest that H2S alleviates Cd toxicity via the improvement of antioxidant system and cellular Cd homeostasis. The up-regulation of antioxidant enzymes by H2S reduced the accumulation of H2O2, and thus decreased Cd influx through the H2O2-activated PM calcium channels. The H2S-simulated vacuolar Cd sequestration was presumably due to the activation of tonoplast Cd(2+)/H(+) antiporters.</AbstractText><CopyrightInformation>Copyright © 2013 Elsevier Masson SAS. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Sun</LastName><ForeName>Jian</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>College of Life Science, Jiangsu Normal University, Xuzhou 221116, Jiangsu Province, PR China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>Ruigang</ForeName><Initials>R</Initials></Author><Author ValidYN="Y"><LastName>Zhang</LastName><ForeName>Xuan</ForeName><Initials>X</Initials></Author><Author ValidYN="Y"><LastName>Yu</LastName><ForeName>Yicheng</ForeName><Initials>Y</Initials></Author><Author ValidYN="Y"><LastName>Zhao</LastName><ForeName>Rui</ForeName><Initials>R</Initials></Author><Author ValidYN="Y"><LastName>Li</LastName><ForeName>Zongyun</ForeName><Initials>Z</Initials></Author><Author ValidYN="Y"><LastName>Chen</LastName><ForeName>Shaoliang</ForeName><Initials>S</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2013</Year><Month>01</Month><Day>28</Day></ArticleDate></Article><MedlineJournalInfo><Country>France</Country><MedlineTA>Plant Physiol Biochem</MedlineTA><NlmUniqueID>9882449</NlmUniqueID><ISSNLinking>0981-9428</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>00BH33GNGH</RegistryNumber><NameOfSubstance UI="D002104">Cadmium</NameOfSubstance></Chemical><Chemical><RegistryNumber>YY9FVM7NSN</RegistryNumber><NameOfSubstance UI="D006862">Hydrogen Sulfide</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D002104" MajorTopicYN="N">Cadmium</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName><QualifierName UI="Q000633" MajorTopicYN="Y">toxicity</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002462" MajorTopicYN="N">Cell Membrane</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006862" MajorTopicYN="N">Hydrogen Sulfide</DescriptorName><QualifierName UI="Q000494" MajorTopicYN="Y">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007425" MajorTopicYN="N">Intracellular Membranes</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D032107" MajorTopicYN="N">Populus</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014617" MajorTopicYN="N">Vacuoles</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2012</Year><Month>11</Month><Day>28</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2013</Year><Month>01</Month><Day>04</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2013</Year><Month>2</Month><Day>19</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2013</Year><Month>2</Month><Day>19</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2013</Year><Month>9</Month><Day>6</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">23416498</ArticleId><ArticleId IdType="pii">S0981-9428(13)00022-3</ArticleId><ArticleId IdType="doi">10.1016/j.plaphy.2013.01.003</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>République populaire de Chine</li></country></list><tree><noCountry><name sortKey="Chen, Shaoliang" sort="Chen, Shaoliang" uniqKey="Chen S" first="Shaoliang" last="Chen">Shaoliang Chen</name><name sortKey="Li, Zongyun" sort="Li, Zongyun" uniqKey="Li Z" first="Zongyun" last="Li">Zongyun Li</name><name sortKey="Wang, Ruigang" sort="Wang, Ruigang" uniqKey="Wang R" first="Ruigang" last="Wang">Ruigang Wang</name><name sortKey="Yu, Yicheng" sort="Yu, Yicheng" uniqKey="Yu Y" first="Yicheng" last="Yu">Yicheng Yu</name><name sortKey="Zhang, Xuan" sort="Zhang, Xuan" uniqKey="Zhang X" first="Xuan" last="Zhang">Xuan Zhang</name><name sortKey="Zhao, Rui" sort="Zhao, Rui" uniqKey="Zhao R" first="Rui" last="Zhao">Rui Zhao</name></noCountry><country name="République populaire de Chine"><noRegion><name sortKey="Sun, Jian" sort="Sun, Jian" uniqKey="Sun J" first="Jian" last="Sun">Jian Sun</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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